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How has the chromatography columns market size evolved in recent years?

In the past few years, the market size for chromatography columns has seen robust growth. It is expected to rise from a value of $8.4 billion in 2024 to $9.09 billion in 2025, witnessing a compound annual growth rate (CAGR) of 8.2%. Factors contributing to this growth during the historical period encompass the expansion of the biopharmaceutical industry, an increasing demand for personalized medicine, environmental testing and monitoring, as well as quality control in the food and beverage sector.

What are the predictions for the chromatography columns market size in the coming years?

Expectations are high for the chromatography columns market size to witness robust growth in the upcoming years. It is projected to expand to $13.16 billion by 2029, with a compound annual growth rate (CAGR) of 9.7%. The growth predicted for the forecast period is due to an increased emphasis on environmental sustainability, the worldwide expansion of pharmaceutical manufacturing, a heightened focus on monolith columns, and the implementation of preparative chromatography. Key trends for the projected period encompass advancements in column technologies, high-performance liquid chromatography, multi-modal chromatography columns, tailor-made chromatography solutions, and collaborations and partnerships.

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What key factors are fueling the growth of the chromatography columns market?

The surge in demand for biopharmaceutical products is anticipated to drive the expansion of the chromatography columns market. Biopharmaceutical products, which are medically beneficial substances derived from biological sources such as humans, animals, or microorganisms, include sugars, proteins, nucleic acids, living cells, or tissues. They are produced either through extraction or partial synthesis from these biological sources. Chromatography columns play a pivotal role in separating and purifying diverse molecules, making sure that the final biopharmaceutical product is pure and devoid of contaminants. For example, data from EuroDev, a private outsourcing company in the Netherlands, revealed in August 2023 that Germany’s biopharmaceutical revenues soared to $1.36 billion (€1.2 billion) in the third quarter of 2022. This marks a growth of 34.0% compared to the same quarter of the previous year. Consequently, the rising demand for biopharmaceutical products is bolstering the growth of the chromatography column market. The upswing in the production of monoclonal antibodies is also predicted to impel the growth of the chromatography column market. Laboratory-created molecules, monoclonal antibodies imitate the immune system’s capability to combat detrimental pathogens, for instance, viruses. In the context of chromatography columns, monoclonal antibodies are proven invaluable for purification, analysis, and characterization of biological samples with unsurpassed specificity and selectivity. As stated in May 2023 by the US-based National Library of Medicine, between December 2021 to October 2022, 10,630,903 (7.3 per 1000) and 18,168,365 (10.8 per 1000) patients in England and Italy respectively, who tested positive for SARS-CoV-2 infection, received 77,469 and 195,604 doses of monoclonal antibodies or antivirals for early treatment of COVID-19, respectively. Consequently, the surge in the production of monoclonal antibodies fuels the expansion of the chromatography column market.

How is the global chromatography columns market divided into key segments?

The chromatography columns market covered in this report is segmented –

1) By Column Type: Normal Phase Chromatography Columns, Prepacked Chromatography Columns, Automated Chromatography Columns

2) By Chromatography Type: Ion Exchange Chromatography, Affinity Chromatography, Gas Chromatography, Gel Filtration, Other Types

3) By Capacity: 1-100 ML, 100-1000 ML, More Than 1L

4) By Application: Sample Preparation, Resin Screening, Protein Purification, Anion And Cation Exchange, Desalting, Other Applications

5) By Industry: Nutraceuticals, Academics, Food And Beverages, Pharmaceuticals, Environmental Biotechnology, Cosmetics, Other Industries

Subsegments:

1) By Normal Phase Chromatography Columns: Silica Columns, Alumina Columns, Other Types Of Normal Phase Columns

2) By Prepacked Chromatography Columns: Disposable Prepacked Columns, Reusable Prepacked Columns

3) By Automated Chromatography Columns: High-Throughput Automated Columns, Standard Automated Columns

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Who are the key firms paving the way for growth in the chromatography columns market?

Major companies operating in the chromatography columns market report are Metrohm AG, Siemens AG, Hitachi Ltd., Thermo Fisher Scientific Inc., Danaher Corporation, Merck KGaA, Corning Incorporated, Tosoh Corporation, Agilent Technologies Inc., Sartorius AG, Shimadzu Corporation, Daicel Corporation, PerkinElmer Inc., Quidel Corporation, Waters Corporation, Bio-Rad Laboratories Inc., Integra LifeSciences Holdings Corporation, Handtmann Group, Hamilton Company, Luminex Corporation, Restek Corporation, Cole-Parmer Instrument Company LLC, Phenomenex Inc., Macherey-Nagel GmbH & Co. KG, Qingdao QShenghan Chemical Co. Ltd., Biotage AB, KNAUER Wissenschaftliche Geräte GmbH, Ace Glass Incorporated, Carl Roth GmbH, Dawn Scientific Inc.

Which trends are expected to transform the chromatography columns market?

Leading businesses in the chromatography column market are producing creative products like size exclusion chromatography (SEC) columns to deliver dependable solutions to clients. SEC columns, filled with porous particles, are utilized to segregate molecules based on size and their capacity to enter and exit these pores. For instance, Waters Corporation, an American firm that manufactures analytical laboratory instruments, introduced new Waters XBridge Premier GTx BEH SEC columns in August 2023. These innovative SEC columns aim to streamline the analysis process and cut costs associated with gene therapies, especially those using adeno-associated viral (AAV) vectors. When these columns are combined with light scattering technology from the Wyatt Technology suite, they provide more comprehensive data in a single test, thereby enhancing the manufacturing of these new gene delivery techniques.

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What regions are contributing significantly to the growth of the chromatography columns market?

North America was the largest region in the chromatography columns market in 2024. Asia Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the chromatography columns market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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